General description
The TLC Explorer Documentation System is designed to
digitally evaluate and record thin-layer chromatography (TLC), boosting the
efficiency and accuracy of chromatography workflows. It provides precise TLC
imaging for reliable densitometric measurement, facilitating quantitative
analysis and consistent data interpretation.
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Features and Benefits
- Digitalized
solution converts spot intensity into numerical data, allowing for
quantitative and qualitative analysis of TLC, HPTLC, and PLC plates.
- Digital
imaging in less than 2 minutes allows for consistent capture of TLC
plates, reducing subjectivity. The software analyzes spots based on pixel
intensity and location, leading to more reliable interpretations.
- Automation
and digitalization help standardize the TLC process, reducing variations
caused by human factors. This leads to greater consistency in analysis and
improved reproducibility.
- Enhanced
documentation and archiving of digital records for saving, sharing, and
retrieving. Researchers can track historical data and compare results over
time more efficiently.
Other Notes
USER-FRIENDLY DESIGN AND OPERATION
The software enables TLC plate analysis in under 2 minutes, with automated
track recognition and simultaneous measurement of multiple plates across a 20 x
20 cm area. It includes features like auto-image rotation for misaligned
plates, background noise reduction filters, and automatic detection of the
starting line and solvent front, with manual adjustment options. Annotations
can be added for extra clarity, and the software supports both comparative and
quantitative examinations of plates.
The device uses three LED light sources—white light (VIS), UV-A (366 nm), and
UV-C (254 nm) — to illuminate the plates from above in direct-light mode and
identify distinct substances. It features glove-compatible touch sensors for
easy operation, a camera, and a PC unit with an antenna, all designed to meet
industrial standards (URS). Connecting to the system is easy via Wi-Fi or QR
code scan for smartphones, laptops, or desktop operation. This plug-and-play
setup requires no technical support. The instrument can also use a power bank
(sold separately) for added portability.
ERGONOMIC VISUAL PLATE ANALYSIS
The TLC Explorer features an inspection window for safe and quick examination
of the plate. A manual shutter slider controls light entry, allowing the user
to adjust visibility and minimize stray light. It provides three types of
excitation sources, easily switched on with a tap on the touch-sensitive
buttons, indicating their wavelengths. However, only one light source can be
active at a time.
SAFETY AND SUSTAINABILITY
The device features a safety setup that prevents UV exposure by ensuring the
analytical process only begins when the plates are secured and closed in the
Drawer Unit. A “Drawer Open” light indicates that the drawer has not been
closed properly. The instrument also uses energy-efficient LED modules instead
of traditional mercury lamps for its light source, providing a more sustainable
and durable option.
EASY MAINTENANCE AND LAMP CHANGE
The exterior of the TLC device is easy to clean with commonly used solvents.
Regular service maintenance is not required. Replacing the lamp unit can be
done with minimal effort. Replacement parts and accessories can be ordered
separately. If you need any further assistance, please contact your local Tech
Service or visit our service webpage: SigmaAldrich.com/TLCservice
WHAT IS INCLUDED:
- TLC
Explorer device including illumination unit and software
- Baseplate
for TLC plates
- Power
plugs for worldwide connection
- Instruction
Manual & "How to Start" Quick Guide
- QR
code sticker for quick connection
- Dust
cover
FREQUENTLY ASKED QUESTIONS (FAQS)
Can the software perform quantification or semi-quantitate analyses:
Yes, it can. The software can calculate concentrations by comparing the spot on
a track with corresponding spots on reference tracks that have known
concentrations.
Is the software tool GMP-compliant:
No, the software is not fully GMP-compliant.
Can the instrument analyze plate formats other than 20 x 10 cm and those with
backings other than glass:
Yes, the instrument accommodates a variety of plate sizes and thicknesses for
added versatility. It supports aluminum- or plastic-backed TLC, HPTLC or PLC
plates with different formats and shapes, up to 20 x 20 cm.
How many different plates can be analyzed in parallel:
You can load several plates or sheets on the base plate, which has an area of
20 x 20 cm at the top of the drawer. The software can analyze multiple plates
in parallel, accurately distinguishing between each one during the
measurements.
Can I also analyze the HPTLC plates:
Yes, the instrument (including software) allows a highly reliable analysis of
HPTLC, TLC, and PLC plates.
Can I run a wavelength scan:
No, unfortunately, this feature is not available. You can carry out excitations
at 254 nm, 366 nm, and VIS wavelengths.
Is there a warranty included:
Yes, we offer a one-year warranty. And in case you encounter any technical
issues, please contact your local representative for further advice.
What is the expected lifetime of the lamp:
The lamp unit is equipped with three LEDs, which have a significantly longer
lifetime and are more sustainable than mercury lamps. The LEDs can last 2-7
years, depending on the hours of usage.
