biological source:
synthetic (inorganic)
Quality Level: 200
product line: ReagentPlus®
Assay: ≥99.5%
Form: powder
storage condition:
(Tightly closed. Dry. Keep in a well-ventilated place. Do
not store near acids.)
technique(s):
cell based assay: suitable
immunohistochemistry: suitable
color: white
mp: 370-425 °C
solubility: soluble
65 g/L at 20 °C (completely)
suitability:
suitable for chromatography
suitable for derivatization
application(s): sample
preparation
SMILES string: [Na]N=[N+]=[N-]
InChI: 1S/N3.Na/c1-3-2;/q-1;+1
InChI key: PXIPVTKHYLBLMZ-UHFFFAOYSA-N
General description
Sodium Azide (NaN3) is a potent inhibitor – a water-soluble
crystalline powder that′s odorless. Widely recognized for its versatile
applications, it plays a pivotal role across molecular biology, cell culture,
and biochemical research. It is also a metabolic inhibitor, which inhibits
oxidative phosphorylation. In cell culture, it maintains the integrity of your
cell lines.
Application
Baylis-Hillman acetates such as ethyl
2-(acetoxyphenylmethyl)acrylate can undergo nucleophilic displacement by sodium
azide in aqueous medium to form ethyl (E)-2-azidomethyl-3-phenylpropenoate.[1]
Sodium azide is suitable for use in histopathology to
prepare and store tissue samples.[2] [3] Also used as a component of
staining buffer (HEPES buffer) for whole mount immunolabelling.[4]
Catalyst for:
- Oxidative
decarboxylation[5]
- Michael
addition reactions[6]
Reagent for synthesis of
- Blue
fluorescent copolymers[7]
- Metal
phosphonates[8]
- Arenes
via aminations[9]
Biochem/physiol Actions
Sodium azide is clinically used as a preservative in
diluting fluid for counting red blood cells.[10] It prevents capping and
internalization of fluorescent surface-bound antibodies in various scientific
applications, including flow cytometry.[11]
Other Notes
For additional information on our range of Biochemicals, please complete this form.
Legal Information
ReagentPlus is a registered trademark of Merck
KGaA, Darmstadt, Germany
